MOAA0101 Assessing individual viral reactivations of the latent reservoir using a novel barcoded virusOral AbstractA14
MOAA0102 Accumulation and persistence of deleted HIV proviruses following prolonged ARTOral AbstractA14
MOAA0103 A subset of extreme HIV controllers is characterized by a small HIV blood reservoir and a weak T cell activation levelOral AbstractA18
MOAA0104 HIV integration sites in CD4 T cells from virally suppressed individuals show clonal expansion but no preferential location in oncogenesOral AbstractA4
MOAA0105 The impact of treatment duration on defective and expanded identical HIV genomes in T cell subsets from peripheral blood and tissuesOral AbstractA14
MOAA0106LB Enrichment of the HIV reservoir in CD32+ CD4 T cells occurs early and is closely associated with immune checkpoint receptor expressionOral AbstractA14
MOAA0201 Sequential receptor-induced conformational states of native membrane-embedded HIV-1 EnvOral AbstractA3
MOAA0202 Optimized Env trimer immunization parameters amplify onset, magnitude and consistency of autologous Tier 2 neutralizing antibody development in nonhuman primatesOral AbstractA32
MOAA0203 Germinal centers monitored by lymph node fine needle aspirates correlate with and predict HIV Tier 2 neutralizing antibody responses after HIV trimer immunizationOral AbstractA30
MOAA0204 Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cowsOral AbstractA43
MOAA0205 Killing of HIV-1-infected cells by neutralizing antibodiesOral AbstractA7
MOAA0206 Allosteric regulation in human anti-HIV-1 Env ADCC-mediating antibodies upon immune complex (IC) formation enhances the binding to FcγRs for the activation of cytotoxicity against HIV-1 virusOral AbstractA8
MOLBPEA01 Majority of HIV virions exclusively express either functional or nonfunctional forms of EnvPoster ExhibitionA1
MOLBPEA02 Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagementPoster ExhibitionA6
MOLBPEA03 Higher levels of NK cell phenotypic diversity and transcriptional activation prior to HIV-1 infection are associated with increased set point viral loadPoster ExhibitionA6
MOLBPEA04 Expanded clones in SIV-infected macaques on antiretroviral therapy recapitulate key features of expanded clones in HIV infection: implications for evaluation of “HIV Cure” interventionsPoster ExhibitionA14
MOLBPEA05 Oxidative stress-related PML nuclear body degradation: a novel pharmacologically druggable mechanism behind the establishment of latency during acute infectionPoster ExhibitionA14
MOLBPEA06 Estimating the contribution of proliferation to HIV-infected lymphocyte persistencePoster ExhibitionA14
MOLBPEA07 Increased levels of HIV-1 specific IgG antibody in the presence of HLA-DPB1*13 in three HIV-1 vaccine trialsPoster ExhibitionA20
MOLBPEA08 Cervicovaginal bacteria and HIV acquisition in young South African womenPoster ExhibitionA21
MOLBPEA09 Medroxyprogesterone acetate, unlike norethisterone, increases R5 HIV-1 replication in ecto- and endocervical explant tissue and PBMCs, at physiologically relevant concentrations, by a glucocorticoid receptor-dependent mechanismPoster ExhibitionA21
MOLBPEA10 HIV-1 up-regulates endogenous Galectin-3 to facilitate virological synapse formation and CD4+ T cell-to-cell transmissionPoster ExhibitionA25
MOLBPEA11 Colorectal distribution of lymphocytes and cell-free HIV surrogate in autologous seminal plasma following simulated anal intercoursePoster ExhibitionA26
MOLBPEA12 Development and in silico evaluation of a novel formulation of oral long-acting antiretroviral therapyPoster ExhibitionA26
MOLBPEA13 Ledgins hamper the establishment of a reactivation competent HIV reservoirPoster ExhibitionA26
MOLBPEA14 A subset of bnAbs exhibit broad binding to primary CD4+ T cells infected with reactivated reservoir HIV in vitroPoster ExhibitionA28
MOLBPEA15 Rapid CTL recognition of HIV-1 latently infected cells depends on the levels of inducible viral reactivation and CTL activation statusPoster ExhibitionA28
MOLBPEA16 CXCR5-transduced primary rhesus macaque CD8 T cells accumulate in B cell follicles in a novel ex vivo B cell follicle migration assayPoster ExhibitionA29
MOLBPEA17 Detection and activation of naive B cells expressing the germline precursors of protective antibodiesPoster ExhibitionA32
MOPDA0101 A higher fraction of drug resistant proviruses express unspliced HIV RNA during ART compared to the archival wild-type proviruses that comprise the HIV-1 reservoirPoster Discussion AbstractA14
MOPDA0102 Evidence of production of HIV-1 proteins from "defective" HIV-1 proviruses in vivo: implication for persistent immune activation and HIV-1 pathogenesisPoster Discussion AbstractA11
MOPDA0103 HIV reservoirs in the brain and association with sex and neurocognitionPoster Discussion AbstractA14
MOPDA0104 Monocyte-derived reactive oxygen species impair CD4+ T cell restoration in HIV-1 patients under therapyPoster Discussion AbstractA11
MOPDA0105 HIV-1-mediated induction of Hypoxia Inducible Factor-1 alpha activity in CD4+ T cells modifies immunometabolic phenotype and decreases cell survivalPoster Discussion AbstractA11
MOPDA0106 Toll-like receptor activation modulates inflammation and HIV-1 infection in the female reproductive tract (FEMINIVI study)Poster Discussion AbstractA9
MOPEA0001 Evidence of substantial HIV-1 genetic evolution in vivo during suppressive therapyPoster ExhibitionA1
MOPEA0002 CRF19_cpx variant emergence in a cluster in naive patients of Southern SpainPoster ExhibitionA1
MOPEA0003 Impact of HLA-associated HIV adaptation on disease progression in MesoamericaPoster ExhibitionA1
MOPEA0004 Heterogeneous age and genetic distribution of within-host HIV-1 reservoirs revealed by a novel phylogenetic dating strategyPoster ExhibitionA1
MOPEA0005 Subtype-specific constraints on HIV-1 adaptation to host cellular immunity revealed through statistical and functional analysesPoster ExhibitionA1
MOPEA0006 Pre-existing tuberculosis infection and associated immune reconstitution inflammatory syndrome affects the HIV-1 reservoirPoster ExhibitionA1
MOPEA0007 Evolution of HIV-1 groups M and O: genetic comparative analysis of 19 HIV-1/MO inter-group recombinant formsPoster ExhibitionA1
MOPEA0008 Proposal for an improved classification of the HIV-1 M subtype A sub-subtypesPoster ExhibitionA1
MOPEA0009 High frequency of non-subtype B infections and clustering in new HIV-1 diagnoses in SpainPoster ExhibitionA1
MOPEA0010 Relative resistance of HLA-B for downregulation by Nef is a fundamental property across lentiviral lineagesPoster ExhibitionA2
MOPEA0011 Characterization of a novel dolutegravir monotherapy-associated S230R Mutation in HIVPoster ExhibitionA2
MOPEA0012 HIV-1 resistance to dolutegravir is modulated by epigenetic signalsPoster ExhibitionA2
MOPEA0013 Impact of immune-driven sequence variation in Pol on viral replication capacity and disease progression in HIV-1 subtype C infectionPoster ExhibitionA2
MOPEA0014 High-resolution mapping and phasing of HIV diversification in humanized micePoster ExhibitionA2
MOPEA0015 Learning evolutionary pathways of HIV-1 subtype C under lopinavir treatmentPoster ExhibitionA2
MOPEA0016 High prevalence of CXCR4-using virus in long lived latently infected naïve and central memory CD4+ T cells in individuals on ARTPoster ExhibitionA3
MOPEA0017 HIV-1 transfer by T cell-macrophage fusion triggers multinucleated giant cell formation for virus spreadingPoster ExhibitionA3
MOPEA0018 Investigation of tandemers activities against cell-associated HIV-1 and against viruses with decreased sensitivity to griffithsinPoster ExhibitionA3
MOPEA0019 Host microRNAs-221 and -222 inhibit HIV-1 entry of macrophages by targeting the CD4 viral receptorPoster ExhibitionA3
MOPEA0020 HIV-1 can enter and integrate the human male germ line, revealing potential for endogenizationPoster ExhibitionA3
MOPEA0021 Regulation of CCR5 conformational states and export by homo-dimerizationPoster ExhibitionA3
MOPEA0022 HIV-1 subtype C may possess extended coreceptor utilization in peripheral blood and the central nervous system of patients experiencing cryptococcal meningitisPoster ExhibitionA3
MOPEA0023 Alternative splicing of human APOBEC3G in HIV infectionPoster ExhibitionA3
MOPEA0024 The role of CCR5 structural diversity in HIV infectionPoster ExhibitionA3
MOPEA0025 Loss of SUN2 impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection in a cyclophilin A-independent mannerPoster ExhibitionA4
MOPEA0026 Insights into the domains of IFITM3 involved in the negative imprinting of HIV-1 viral particles infectivityPoster ExhibitionA4
MOPEA0027 Apolipoprotein E is an HIV-1-inducible restriction factor of HIV-1Poster ExhibitionA4
MOPEA0028 A structural study of UNG2 and its interaction with the HIV protein VprPoster ExhibitionA4
MOPEA0029 Regulation of retroviral integration by RNA polymerase II associated factors and chromatin structurePoster ExhibitionA4
MOPEA0030 Autophagy does not influence HIV replication in productively infected dendritic cells (DCs)Poster ExhibitionA4
MOPEA0031 p21 restricts HIV-1 replication in dendritic cells through the synergistic reduction of dNTP biosynthesis and the regulation of SAMHD1 antiviral activityPoster ExhibitionA4
MOPEA0032 Expression of native HIV-1 antisense protein (ASP) in chronically infected T cells (ACH-2) following stimulation with TNF-αPoster ExhibitionA5
MOPEA0033 Inhibition of HIV-1 gene transcription by KAP1: a new CTIP2 interactantPoster ExhibitionA5
MOPEA0034 Translational regulation of APOBEC3G mRNA by Vif requires its 5'UTR and contributes to restoring HIV-1 infectivityPoster ExhibitionA5
MOPEA0035 TILRR is a potential enhancer of inflammation and HIV-1 vaginal infection through interacting with NFκB signaling pathwayPoster ExhibitionA5
MOPEA0036 HIV-1 Vpr counteracts CTIP2-mediated cellular response to viral infectionsPoster ExhibitionA5
MOPEA0037 BRD4 inhibitor, JQ1, but not HDAC inhibitors, stimulate accumulation of spliced HIV RNAPoster ExhibitionA5
MOPEA0038 Generation of HIV latency reporter cell lines by targeted genome engineering to explore effects of proviral integration site choicePoster ExhibitionA5
MOPEA0039 HIV-1 Gag interaction with Dicer and consequences on the miRNA processing and binding to the RNA interference complexPoster ExhibitionA5
MOPEA0040 Microglial cells that are latently infected by HIV are activated by inflammatory stimuli and induce neuronal damagePoster ExhibitionA5
MOPEA0041 A single-cell method to detect early activation of the latent HIV provirusPoster ExhibitionA5
MOPEA0042 The nuclear pore orchestrates HIV-1 nuclear import and sculpts the chromatin landscape near integration sitesPoster ExhibitionA5
MOPEA0043 Host factors associated to control of HIV-reservoir in elite controller patientsPoster ExhibitionA14
MOPEA0044 Peripheral T follicular helper cells make a difference in HIV reservoir size between elite controllers and patients on successful ARTPoster ExhibitionA14
MOPEA0045 HIV-1 integration sites reveal heterogeneity in the latent population and explain the limited induction of latent provirusesPoster ExhibitionA14
MOPEA0046 HIV reservoir size and composition, after antiretroviral treatment initiation, is related to HIV-specific CD8+ T-cell responses developed during primary HIV infectionPoster ExhibitionA14
MOPEA0047 Urethral tissue macrophages are genuine viral reservoirs in HIV-1-infected individuals under suppressive antiretroviral therapyPoster ExhibitionA14
MOPEA0048 Stimulation of the HIV T-cell reservoir leads to expression of genetically intact but functionally impaired Env glycoproteinsPoster ExhibitionA14
MOPEA0049 Early initiation of antiretroviral treatment post SIV infection does not resolve lymphoid tissue activationPoster ExhibitionA14
MOPEA0050 A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro VOA in detecting latently infected cells from patients on ART with undetectable viral loadsPoster ExhibitionA14
MOPEA0051 Suppressive myeloid cells of the human testicular interstitium: implication for HIV-1 persistencePoster ExhibitionA14
MOPEA0052 Analysis of microRNA differential expression patterns during HIV-1 reactivation to identify new molecules involved in HIV-1 latencyPoster ExhibitionA14
MOPEA0053 Intact HIV-1 provirus is enriched in effector memory and HLA-DR+ memory CD4+ T cellsPoster ExhibitionA14
MOPEA0054 Inhibition of HIV-1 replication in macrophages by the neuropeptides VIP and PACAP: analysis of the inhibitory potential and mechanismsPoster ExhibitionA14
MOPEA0055 Major contribution to HIV reservoirs of peripheral blood T follicular helper cells in HIV treated patients with low HIV reservoirsPoster ExhibitionA14
MOPEA0056 Contribution of peripheral blood and colon myeloid cells to HIV persistence during ARTPoster ExhibitionA14
MOPEA0057 Ultrasensitive HIV-1 p24 detects single infected cells and differences in reservoir induction by latency-reversal agentsPoster ExhibitionA14
MOPEA0058 The mammalian target of rapamycin is a druggable key regulator of HIV-1 permissiveness in gut-homing CCR6+ Th17 cellsPoster ExhibitionA14
MOPEA0059 Massive full-length, next generation sequencing identifies clonally-expanded, genome-intact replication-competent HIV-1 in Th1 cellsPoster ExhibitionA14
MOPEA0060 Role of peroxisome proliferator activated receptor-gamma in regulating inflammatory signalling in HIV-1 associated brain inflammationPoster ExhibitionA14
MOPEA0061 Factors associated with increased number of unique integration sites during early ARTPoster ExhibitionA14
MOPEA0062 Characterization of the active viral reservoir by a novel single cell RNA FISH-flow method in samples from HIV-infected individualsPoster ExhibitionA14
MOPEA0063 The lungs as anatomical reservoirs of HIV: enrichment in HIV-infected cells and skewed T-cell distribution in the lungs of HIV-infected adults under suppressive ARTPoster ExhibitionA14
MOPEA0064 Memory CD4+CD45RO+SAMHD1low cells exhibit distinct genes profile and contain the highest level of HIV-1 DNA with segregated HIV-1 populationsPoster ExhibitionA14
MOPEA0065 2LTR circle dynamics during integrase inhibitor monotherapy in the presence and absence of CD8+ cellsPoster ExhibitionA14
MOPEA0066 HIV reservoirs in developing countries: implication for HIV CURE strategiesPoster ExhibitionA14
MOPEA0067 In vivo massive expansion of a T-cell clone carrying a defective HIV genome: implication for the measurement of the HIV reservoirPoster ExhibitionA14
MOPEA0068 Inhibition of HIV-1 infection by bi-specific immunoadhesin-IgA in humanized micePoster ExhibitionA21
MOPEA0069 The male organs source of AIDS virus in semen uncovered through phylogenetic analysisPoster ExhibitionA21
MOPEA0070 HIV cell-associated transmission in the colo-rectal mucosa ex vivo and its modulation by seminal plasmaPoster ExhibitionA21
MOPEA0071 Vaginal bacteria modify HIV pre-exposure prophylaxis efficacy in African womenPoster ExhibitionA21
MOPEA0072 Human seminal plasma from HIV-1-infected patients induces migration of mucosal dendritic cells and alters integrity of intestinal epitheliumPoster ExhibitionA21
MOPEA0073 A combination of broadly neutralizing antibodies prevents in vitro SHIV162P3 cell-free transmission more efficiently than cell-to-cell transmissionPoster ExhibitionA21
MOPEA0074 Intestinal dendritic cells and macrophages play a different role in the early events of HIV-1 transmissionPoster ExhibitionA21
MOPEA0075 Virological synapses formed between HIV-1-infected CD4+ T-cells and mucosal epithelium promote macrophage infection followed by reservoir formation in reconstructed urethral tissuesPoster ExhibitionA21
MOPEA0076 HIV and biologic sex differences in the risk of mother to child transmission in CameroonPoster ExhibitionA22
MOPEA0077 Properties of ENV derived from transmitted HIV-1 issued from transmission clustersPoster ExhibitionA24
MOPEA0078 Gut-homing Δ42PD1+Vδ2 T cells promote innate mucosal damage via TLR4 during acute HIV-1 infectionPoster ExhibitionA25
MOPEA0079 In depth sampling of high-risk populations to characterize HIV transmission epidemics among young MSM using PrEP in France and QuebecPoster ExhibitionA25
MOPEA0080 Very early treated acute HIV patients have high naïve-CD4+Tregs recovery with a decreased immune activationPoster ExhibitionA25
MOPEA0081 Low frequencies of HIV-infected cells in blood, colon and lymph node at the earliest stage of acute infection (Fiebig I)Poster ExhibitionA25
MOPEA0082 T follicular helper cells are preserved by ART and correlate with reservoir size in early HIV infectionPoster ExhibitionA25
MOPEA0083 Evidence of fast normalization of inflammation biomarkers after ART started during acute, but not in early chronic HIV infectionPoster ExhibitionA25
MOPEA0084 IL-7 is UP-regulated in the ileal mucosa during hyperacute siv infection in Chinese rhesus macaques, triggering local chemokine expressions and immune cell migrationsPoster ExhibitionA25
MOPEA0085 Deep sequencing reveals viral evolution in Gag within protective HLA alleles B*57:02, B*58:01 and B*7 supertype individuals acutely infected with HIV-1 subtype C in Durban, South AfricaPoster ExhibitionA25
MOPEA0086 NKp30 and its ligands: emerging players in HIV-2-infected patientsPoster ExhibitionA35
MOPEA0087 Prevalence and risk factors associated with HIV/viral hepatitis B and C co-infections among people who inject drugs in Mozambique, 2013-2014Poster ExhibitionA36
MOPEA0088 A New HIV/HBV co-infection model: hepatocytic expression of human sodium taurocholate cotransporting polypeptide (NTCP) enables hepatitis B virus infection of macaquesPoster ExhibitionA36
MOPEA0089 Hepatitis B virus infection in HIV-1 negative and positive pregnant women in Botswana, implications for HBV vertical transmissionPoster ExhibitionA36
MOPEA0090 Burden of HCV mono-infections and HCV/HIV co-infections in four provinces in CambodiaPoster ExhibitionA36
MOPEA0091 Dysregulation of IL-7/IL-7 receptor signaling pathway in memory CD8 T cells predicts cryptococcosis-associated immune reconstitution inflammatory syndromePoster ExhibitionA38
MOPEA0092 Impact of minority variants on the virological response to a rilpivirine-based first-line regimenPoster ExhibitionA40
MOPEA0093 Primary HIV-1 drug resistance by massive parallel sequencing among treatment naïve HIV-infected blood donorsPoster ExhibitionA40
MOPEA0094 A bioinformatic approach to determining HIV-1 drug resistance profiles in next-generation sequencing datasetsPoster ExhibitionA40
TUAA0101 Evaluation of memory CD8+ T cell responses in individuals initiating cART during hyperacute HIV-1 infectionOral AbstractA8
TUAA0102 Early anti-SIV CD8+ T cell antiviral activity is associated with durable elite control of SIV infection in macaques carrying or not protective MHC alleles: the ANRS SIC studyOral AbstractA42
TUAA0103 CD8+ T cell depletion leads to a different profile of SIV viral decay under integrase inhibitor monotherapyOral AbstractA8
TUAA0104 Memory-like NK cells exploit innate priming and alternative signaling mechanisms to enhance function and mobilize at HIV/SIV mucosal portals of entryOral AbstractA6
TUAA0105 The human penis is an immunologically active tissue: a preliminary study on the development of an HIV vaccineOral AbstractA9
TUAA0106LB Efficacy of epithelial stem cell-based AIDS vaccine to induce mucosal immune responses offering protection against SIV challenge in macaquesOral AbstractA32
TUPDA0101 Combined IL-21 and IFNα treatment limits residual inflammation and delays viral rebound in SIV-infected macaquesPoster Discussion AbstractA28
TUPDA0102 Interleukin (IL)-27 induces HIV-resistance in T cells and dendritic cells via different mechanisms: identification of YB-1 and ANKRD22 as novel host dependency factorsPoster Discussion AbstractA29
TUPDA0103 Increased effector cytotoxic lymphocytes in lymph nodes of hetIL-15 treated macaques suggest potential to disrupt SIV/HIV reservoirsPoster Discussion AbstractA33
TUPDA0104 The human IL-15 superagonist ALT-803 activates NK and memory T cells, reactivates latent SIV and drives SIV-specific CD8+ T cells into B cell folliclesPoster Discussion AbstractA29
TUPDA0105 Tissue factor pathway inhibitor Ixolaris improves disease outcome in progressive SIVsab-infected pigtail macaquesPoster Discussion AbstractA16
TUPDA0106 Engineering HIV immunity with a chimeric antigen receptor in the non-human primate modelPoster Discussion AbstractA29
TUPEA0095 Negative checkpoint regulatory molecule 2B4 (CD244) contributes to iNKT cell dysfunction during HIV infectionPoster ExhibitionA6
TUPEA0096 NK cell subset frequency and developmental markers are altered in HIV-1+ pregnanciesPoster ExhibitionA6
TUPEA0097 Differential distribution of M1 and M2 macrophages in the decidua and chorionic villi of placentas from HIV-1-infected mothers on combination antiretroviral therapyPoster ExhibitionA6
TUPEA0098 Influence of the genetic LILRA3-deletion on HIV and Hepatitis CPoster ExhibitionA6
TUPEA0099 Sensing of HIV-1 entry triggers a type I interferon response in human primary macrophagesPoster ExhibitionA6
TUPEA0100 In vivo analysis of LILRB2 on dendritic cells reveals specific up-regulation in early phase of SIV / HIV infection: implication in anti-viral immune responsesPoster ExhibitionA6
TUPEA0101 Allogeneic NK-CD4 co-cultures reveal potential protective KIR/HLA mechanisms against HIVPoster ExhibitionA6
TUPEA0102 HIV-1 Vif adaptation to host immune pressure impact of cytidine deaminases and host HLAPoster ExhibitionA6
TUPEA0103 Blood precursor DCs are the most efficient transmitters of HIV-1 to T cellsPoster ExhibitionA6
TUPEA0104 SUMOylation influences the sensitivity of SAMHD1 to Vpx-mediated degradationPoster ExhibitionA6
TUPEA0105 Interplay between infection and innate sensing mechanisms of the HIV vaccine vector MVA in human dendritic cellsPoster ExhibitionA6
TUPEA0106 Plasmacytoid dendritic cells (pDC) produce Interferon-λ intrinsically, whereas BDCA3+ DC rely on cellular cross-talk, in response to HIV-1 and HIV-2Poster ExhibitionA6
TUPEA0107 Comparison of genital tract immune mediators between HIV-infected and HIV-uninfected Malawian women randomized to the depot medroxyprogesterone acetate injectable or levonorgestrel implantPoster ExhibitionA9
TUPEA0108 Seminal plasma exposures strengthen vaccine responses in the female reproductive tract mucosaePoster ExhibitionA9
TUPEA0109 Mucosal neutrophil activation is associated with gastrointestinal and systemic T-cell activationPoster ExhibitionA9
TUPEA0110 T cell immune exhaustion in gut-associated lymphoid tissue during treated primary HIV infection: implications for HIV persistencePoster ExhibitionA9
TUPEA0111 Impaired genital wound-healing pathways in women experiencing chronic sexual abuse: implications for HIV acquisitionPoster ExhibitionA9
TUPEA0112 Distribution and phenotype characterization of HIV-specific CD8 T cells in situ in the rectal mucosa of HIV+ elite controllersPoster ExhibitionA9
TUPEA0113 Sexually transmitted infections (STIs) increase levels of cytokine and cellular biomarkers of HIV riskPoster ExhibitionA9
TUPEA0114 Potential immune mechanism for the relationship between HIV risk and multiple concurrent HPV infectionsPoster ExhibitionA9
TUPEA0115 Degranulating immune cells are associated with higher viral load at cervico-vaginal surface of HIV-infected women in IndiaPoster ExhibitionA9
TUPEA0116 Early antiretroviral therapy (ART) initiation improves gut mucosal immunity in SIV-infected Chinese rhesus macaquesPoster ExhibitionA9
TUPEA0117 PD-1, KLRG1, and EomesoderminHigh as potential markers of CD8+ T-cell exhaustion in rectal mucosa during chronic HIV infectionPoster ExhibitionA9
TUPEA0118 Enhancement of HIV-1 spreading and persistence by MIF/CD74 interaction in primary monocyte-derived macrophages (MDM) and CD4+ T-lymphocytes (CD4TL) in vitroPoster ExhibitionA11
TUPEA0119 Expression and role of chemokine fractalkine in HIV neuro-pathogenesis: a new approach to understand and treat HANDPoster ExhibitionA11
TUPEA0120 Fatty acid profiles altered by HIV infection persist despite suppressive antiretroviral therapy (ART) and are associated with immune activation in the ACTG 5248 studyPoster ExhibitionA11
TUPEA0121 IP-10 and IL-18 are good markers of persistent inflammation in HIV-1 elite controllersPoster ExhibitionA11
TUPEA0122 Combination antiretroviral therapy has minimal effect on the HIV-associated expansion of adaptive, memory-like NK cells and NK cell activationPoster ExhibitionA11
TUPEA0123 Platelets of HIV-infected patients release a large amount of Growth-regulated Oncogence Alpha (GRO-a): a chemokine stimulating HIV replicationPoster ExhibitionA11
TUPEA0124 Altered macrophage phenotype in HIV-infection may contribute to vascular inflammationPoster ExhibitionA11
TUPEA0125 High cannabis levels associated with decreased T cell activation in HIV-infected individualsPoster ExhibitionA11
TUPEA0126 Upregulation of chronic inflammatory cytokines despite early treatment and virological suppression in children: a role in HIV persistence?Poster ExhibitionA11
TUPEA0127 CD49d expression in T-lymphocytes subsets and cardiovascular risk in HIV-positive subjectsPoster ExhibitionA11
TUPEA0128 Host determinants associated to immunological non-response in patients on cARTPoster ExhibitionA12
TUPEA0129 Chronic immune activation as a cause of poor T‑helper cell migration in successfully ART‑treated HIV-1-infected individualsPoster ExhibitionA12
TUPEA0130 Reduced naïve CD8+ T-cell priming efficacy in HIV-infected patientsPoster ExhibitionA12
TUPEA0131 Pre-senescent state of hematopoietic progenitors from HIV-1-infected treated patients with immunological failurePoster ExhibitionA12
TUPEA0132 Microbial dysbiosis does not alter immune activation or disease progression in SIV-infected Asian macaquesPoster ExhibitionA13
TUPEA0133 Nadir CD4+ T-cell count strongly predicts gut disbyosis in HIV infectionPoster ExhibitionA13
TUPEA0134 Gut dysbiosis during acute HIV infectionPoster ExhibitionA13
TUPEA0135 High levels of polymicrobial vaginal communities and genital inflammation in HIV-infected womenPoster ExhibitionA13
TUPEA0136 High abundance of Prevotella in gut microbiota of perinatally HIV-infected children despite suppressive antiretroviral therapy is indirectly associated with CD4 T cellsPoster ExhibitionA13
TUPEA0137 The study of gorilla enteric virome dynamics: association with SIV infectionPoster ExhibitionA13
TUPEA0138 Changes in the gut and blood microbiome after starting antiretroviral therapy in HIV-1-infected patientsPoster ExhibitionA13
TUPEA0139 Effect of HIV on the rectal microbiome in the Chicago site of the Women's Interagency HIV Study (WIHS)Poster ExhibitionA13
TUPEA0140 Alterations in dendritic cells status and B cell subsets in HIV-1-infected children at different stages of diseasePoster ExhibitionA15
TUPEA0141 Epigenetic dysregulation of the major histocompatibility complex region in HIV-infected children on antiretroviral therapyPoster ExhibitionA15
TUPEA0142 Biomarkers of progression after HIV acute/early infection: nothing compares to CD4+ T-cell count?Poster ExhibitionA15
TUPEA0143 Illicit drug use alters the composition and HIV inhibitory function of semen exosomesPoster ExhibitionA15
TUPEA0144 Multiple effects of nef on host by-stander cells: from cholesterol metabolism to epigenetic changesPoster ExhibitionA16
TUPEA0145 Comorbidities in people living with HIV (PLWHIV) compared to general population: an epidemiological analysis using a claims database in FrancePoster ExhibitionA16
TUPEA0146 Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controller patientsPoster ExhibitionA18
TUPEA0147 Older age at infection is associated with long-term non-progression in women infected with non-subtype B HIV-1Poster ExhibitionA18
TUPEA0148 Decrease of blood HIV reservoirs over years in HIV-controllersPoster ExhibitionA18
TUPEA0149 Post treatment control in an adult with perinatally acquired HIV following cessation of antiretroviral therapyPoster ExhibitionA18
TUPEA0150 Follicular helper t cell function sustains high-level specific memory B cell responses in sponstaneously controlled HIV infectionPoster ExhibitionA18
TUPEA0151 Exome-wide association study in HIV-infected individuals identifies a functional variant related to long-term non progression in UBXN6Poster ExhibitionA18
TUPEA0152 Compromised macrophage-mediated HIV trans infection of CD4 T cells is linked to lipid raft dissociationPoster ExhibitionA18
TUPEA0153 Functional characterization of a public TCR clonotype identified against the HIV-1 Gag A2-FK10 epitopePoster ExhibitionA18
TUPEA0154 Evaluation of combined protective effect of five variant genotypes on susceptibility to HIV infection in discordant couplesPoster ExhibitionA19
TUPEA0155 Interleukin-21/microRNA-29 axis in natural resistance to HIV-1 infectionPoster ExhibitionA19
TUPEA0156 Immune signatures linked with HIV-1 neutralization breadthPoster ExhibitionA20
TUPEA0157 Preservation of lymphopoietic potential and virus suppressive capacity by CD8+ T cells in HIV-2-infected controllersPoster ExhibitionA20
TUPEA0158 HLA-C expression levels and binding stability to β2m modulate HIV-1 infectivityPoster ExhibitionA20
TUPEA0159 HIV-specific CD8+ T cells from natural HIV-1 controllers have a distinct signature associated with enhanced metabolic plasticity and antiviral function. ANRS CO21 CODEXPoster ExhibitionA20
TUPEA0160 Functionality of tissue-resident SIV-specific CD8+ T cellsPoster ExhibitionA20
TUPEA0161 NK cell capacity to accumulate in lymph node follicles is associated with SIV controlPoster ExhibitionA42
TUPEA0162 Dolutegravir-based simplification of antiretroviral therapy (mono- and dual therapy) in humanized mice with chronic HIV infectionPoster ExhibitionA42
TUPEA0163 Modeling viral kinetics predicts a rapid establishment of the cytotoxic immune response targeting distinct infected cell compartments in SIV controller macaques (ANRS SIC study)Poster ExhibitionA42
TUPEA0164 RNA-Seq reveals lymph node resident pDCs as the primary cellular producer of type I IFN in SIV infectionPoster ExhibitionA42
WEAA0101 Impaired Nef's ability to counteract SERINC5 is associated with decreased plasma viremiaOral AbstractA4
WEAA0102 HIV-1 concentrates and shelters cell-associated infectivity a “viral biofilm”Oral AbstractA14
WEAA0103 Coordinated mTOR-mediated rewiring of nucleotide anabolism regulates HIV-1 infection of CD4 T lymphocytesOral AbstractA4
WEAA0104 Membrane-associated RING-CH (MARCH) 1 and 2 are other members of MARCH proteins that inhibit HIV-1 infectionOral AbstractA3
WEAA0105 Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infectionOral AbstractA4
WEAA0106LB Identification of a new factor involved in DNA methylation-mediated repression of latent HIV-1Oral AbstractA5
WEAA0201 Investigating the SHIV reservoir in a non-human primate model following allogeneic bone marrow transplantationOral AbstractA28
WEAA0202 Investigating clinical therapeutics to target infected cells and promote HIV clearanceOral AbstractA28
WEAA0203 Inhibiting memory CD4+ T-cell self-renewal to reduce HIV persistenceOral AbstractA28
WEAA0204 PBMCs from patients with chronic myeloid leukemia treated with different tyrosine kinase inhibitors show variable susceptibility to HIV-1 infection: searching for the best therapeutic approachOral AbstractA28
WEAA0205 Eradication without reactivation: suppression of HIV-1 transcription and reactivation from latency by a Tat inhibitorOral AbstractA28
WEAA0206 Myeloablative conditioning is dispensable for transplant-dependent HIV cureOral AbstractA28
WEPDX0104 Phylodynamic insights into HIV epidemic dynamics within CanadaPoster Discussion AbstractA1
WEPDX0105 Phylogenetics between and within hosts along the genome reveals transmission, dual infections, recombination and contaminationPoster Discussion AbstractA1
WEPDX0106 Deep analysis of HIV transmission chains: input of ultra-deep sequencingPoster Discussion AbstractA1
WEPEA0165 Activity of mannose-binding lectins to enhance virus neutralization by antibodies to V1V2 and V3 loops of HIV-1 envelopePoster ExhibitionA7
WEPEA0166 IL-33 enhances the induction, durability, and breadth of the antibody response to a DNA/protein-based HIV Env vaccinePoster ExhibitionA7
WEPEA0167 Non-neutralizing antibodies targeting HIV's V1V2 domain exhibit strong inhibitory activitiesPoster ExhibitionA7
WEPEA0168 Antibody dependent cell-mediated phagocytic activity is increased in the genital tract mucosae of HIV-infected women with prior tenofovir gel exposurePoster ExhibitionA7
WEPEA0169 HIV-specific B cell frequency correlates with transmitted/founder virus neutralization in patients naturally controlling HIV-infectionPoster ExhibitionA7
WEPEA0170 Early recovery of antibody-mediated neutralization and ADCC responses in HIV-positive individuals under dolutegravir-based antiretroviral therapyPoster ExhibitionA7
WEPEA0171 Post-translational processing influences antibody reactivity against the gp120 V2 domain on infected CD4+ T cellPoster ExhibitionA7
WEPEA0172 A unique N332 supersite directed bnAb from a slow progressor shares characteristics with both CD4bs and V3-glycan bnAbsPoster ExhibitionA7
WEPEA0173 Antibody dependent cellular cytotoxicity and neutralization antibody responses in HIV-1-infected elite controllersPoster ExhibitionA7
WEPEA0174 Identification and characterization of broadly neutralizing antibodies against founder virusesPoster ExhibitionA7
WEPEA0175 The impact of HIV-genetics on imprinting HIV-1 neutralization and binding responsesPoster ExhibitionA7
WEPEA0176 Neutralizing antibodies efficiently inhibit HIV transmission from infected T cells to heterologous DC and T cellsPoster ExhibitionA7
WEPEA0177 Suppression of SAMHD1 in dendritic cells improves antigen presentation and HIV-specific cytolytic T cell response in vitroPoster ExhibitionA8
WEPEA0178 Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptationPoster ExhibitionA8
WEPEA0179 Control of HIV-1 by HLA-B*52:01-restricted or C*12:02-restricted cytotoxic T lymphocytes specific for 6 epitopes in an HIV-1-infected Japanese cohort, in which HLA-B*57 and HLA-B*27 are very rarePoster ExhibitionA8
WEPEA0180 Follicular cytotoxic T cells specifically control the infection in follicular helper T cellsPoster ExhibitionA8
WEPEA0181 Low T cell immunogenicity of the yellow fever vaccine in HIV-infected patients: ANRS EP46 NOVAAPoster ExhibitionA8
WEPEA0182 Heterogeneity of circulating follicular helper T cells during hyperacute HIV-1 subtype C infection impact neutralizing antibody responsesPoster ExhibitionA8
WEPEA0183 CD8+ T-cell suppressive capacity directly correlates with peak viral load in a cohort of virally suppressed HIV+ patients on combination antiretroviral therapyPoster ExhibitionA8
WEPEA0184 Early antiretroviral therapy intervention in HIV infection can rescue metabolic profiles of ex vivo CD8+ T cellsPoster ExhibitionA8
WEPEA0185 Unilateral selection of viral mutations for escape from CD8+ T-cell recognition in SIV infectionPoster ExhibitionA10
WEPEA0186 HLA-C is downregulated by most primary clones of HIV-1, and variation between these viruses is more pronounced for downregulation of HLA-C than HLA-A/BPoster ExhibitionA10
WEPEA0187 HIV-1 accessory proteins hijack membrane trafficking to downregulate CD28Poster ExhibitionA10
WEPEA0188 Hide and seek with HIV-1 Nef: gaining super-resolution insights to immune evasionPoster ExhibitionA10
WEPEA0189 Deep sequencing analyses of emergence and maintenance of mutations in CTL epitopes of HIV-controllers with differential control of ViremiaPoster ExhibitionA10
WEPEA0190 Pre-clinical pharmacokinetics of elsulfavirine/VM1500A long acting injectable formulationsPoster ExhibitionA26
WEPEA0191 Generation of phage recombinant single chain variable fragment (scFv) library from pooled PBMCs of HIV-1-infected humans and identification of cross-neutralizing anti-CD4 binding site and N332 glycan dependent scFvsPoster ExhibitionA26
WEPEA0192 Complete protection of HIV-1 infection by a tandem BiIA in humanized mice and rhesus macaquesPoster ExhibitionA26
WEPEA0193 Ranpirnase exhibits dose-dependent inhibition of rectal explant HIV infection and inflammatory changesPoster ExhibitionA26
WEPEA0194 A comparison study of tenofovir alafenamide (TAF) plus emtricitabine (FTC) in solution and as nanoparticles (NPs) for pre-exposure prophylaxis (PrEP) in humanized BLT (hu-BLT) micePoster ExhibitionA26
WEPEA0195 Bevirimat-like compounds overcome HIV resistance and target different infection stepsPoster ExhibitionA26
WEPEA0196 Synthesis and properties of novel soluble bifunctional CD4-mimetic small molecules containing pyridine moietyPoster ExhibitionA26
WEPEA0197 A novel therapeutic approach to prevent AIDSPoster ExhibitionA26
WEPEA0198 Novel selection approaches to identify broadly neutralizing DARPins targeting the HIV-1 envelope proteinPoster ExhibitionA26
WEPEA0199 Triterpene-resistant HIV env variants show higher sensitivity to anti-V3 neutralizing antibodiesPoster ExhibitionA26
WEPEA0201 New formulation of injectable and removable long-acting dolutegravir is effective in prevention of HIV transmission with high dose vaginal HIV challengesPoster ExhibitionA26
WEPEA0202 A novel NRTI, EFdA, effectively penetrates and suppresses HIV infection in all individual compartments of male genital tractPoster ExhibitionA26
WEPEA0203 Preclinical characterization of a potent D-peptide inhibitor of HIV entry: cholesterol-conjugated PIE12-trimer (CPT31)Poster ExhibitionA26
WEPEA0204 RNA-induced epigenetic silencing of HIV-1 involves actin regulators, Arp2 and Formin-like 1 proteinPoster ExhibitionA27
WEPEA0205 Characterization of novel and potent U1 interference RNAs targeting the Gag open reading frame of HIV-1Poster ExhibitionA27
WEPEA0206 A new highly sensitive retinoic acid-based viral outgrowth assay to detect replication-competent HIV reservoirPoster ExhibitionA28
WEPEA0207 The PPARγ antagonism inhibits HIV replication while restoring effector functions in Th17 cellsPoster ExhibitionA28
WEPEA0208 HIV-1-specific ADCC following anti-latency therapy and analytical treatment interruptionPoster ExhibitionA28
WEPEA0209 Sphingosine-1-phosphate receptor 1 agonists as HIV-1 latency reversing agentsPoster ExhibitionA28
WEPEA0210 Monocyte co-culture can reverse pre-activation but not post-activation latencyPoster ExhibitionA28
WEPEA0211 The activation of NF-kB and the subsequent transcription of latent HIV-1 in resting CD4+ T cells is the direct consequence of MVC binding to CCR5Poster ExhibitionA28
WEPEA0212 Antiretroviral drug transporters and metabolic enzymes expressed in the testes could potentially contribute to low tissue drug concentrations and HIV-1 persistencePoster ExhibitionA28
WEPEA0213 Blood CXCR3+ CD4 T cells are enriched in inducible replication competent HIVPoster ExhibitionA28
WEPEA0214 Latency reversing agents induce differential responses in distinct memory CD4+ T cell subsets in virally suppressed individualsPoster ExhibitionA28
WEPEA0215 A novel strategy to circumvent cytokine release associated with HIV latency reversalPoster ExhibitionA28
WEPEA0216 Early initiation of long-term ART may favor interventions to eradicate HIV: analysis of cell turnover and persistent HIV reservoir in distinct CD4+ T cell subpopulations in suppressed HIV diseasePoster ExhibitionA28
WEPEA0217 Replication competent HIV reservoirs resist elimination by CTLs and potent combinations of latency-reversing agentsPoster ExhibitionA28
WEPEA0218 4-Deoxyphorbol derivatives as new drug candidates for “Shock and Kill” therapy with strong activity against HIV-1Poster ExhibitionA28
WEPEA0219 Stress increases HIV transcription in HIV-infected individuals on antiretroviral therapy: implications for biomarkers of HIV persistencePoster ExhibitionA28
WEPEA0220 HIV-1 Nef blockade improves the immune recognition and clearance of primary latently HIV-1-infected CD4 T cells by autologous CD8 T cellsPoster ExhibitionA28
WEPEA0221 Panobinostat distribution in rhesus macaque lymph nodes following anti-latency therapyPoster ExhibitionA28
WEPEA0222 Vorinostat renders the replication-competent latent reservoir of HIV vulnerable to clearance by CD8 T cellsPoster ExhibitionA28
WEPEA0223 HIV-1 Nef is required for efficient latency reversal in a T cell linePoster ExhibitionA28
WEPEA0224 IFITM1 targets HIV-1 latently infected cells for antibody dependent cytolysisPoster ExhibitionA28
WEPEA0225 Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infectionPoster ExhibitionA28
WEPEA0226 The central nervous system as a reservoir of HIV-1 variants resistant to broadly neutralizing antibodiesPoster ExhibitionA29
WEPEA0227 Knockdown of CCR5 expression in antigen-specific CD4 T cellsPoster ExhibitionA29
WEPEA0228 Structures within the coreceptor binding site account for the broad neutralizing activity of single chain variable fragments (scFv) targeting CD4-induced epitopesPoster ExhibitionA29
WEPEA0229 Jak inhibitors employ novel mechanisms to block reservoir seeding and HIV persistencePoster ExhibitionA29
WEPEA0230 CTL-based vaccine-induced control is associated with induction of high follicular to extra-follicular ratios of virus-specific CD8+ T cellsPoster ExhibitionA30
WEPEA0231 Deciphering the first steps of the local immune response after intradermal vaccination with recombinant MVAPoster ExhibitionA30
WEPEA0232 Innate myeloid responses are highly diverse and strongly differ after the priming and the boosting immunizationsPoster ExhibitionA30
WEPEA0233 Novel pDNA prime-boost vaccine strategy combining gag and Env elicits broad cytotoxic T cell and antibody responses targeting conserved subdominant gag and Env epitopes of HIV and SIVPoster ExhibitionA30
WEPEA0234 Effective priming of CD8+ T cells with ability to suppress HIV-1 replication using STING ligandPoster ExhibitionA31
WEPEA0235 Use of encapsulated NOD2 ligands for increasing germinal centers and enhancing HIV humoral responsesPoster ExhibitionA31
WEPEA0236 Delivery of antigen to nasal-associated lymphoid tissue microfold cells through secretory IgA targeting local dendritic cells confers protective immunityPoster ExhibitionA32
WEPEA0237 HIV-1 conserved mosaics delivered by regimens with integration-deficient, DC-targeting lentiviral vector induce robust T cellsPoster ExhibitionA32
WEPEA0238 Langerhans cells targeted with anti-Langerin monoclonal antibodies fused with HIV antigens promote the differentiation of naïve CD4+ T cells towards Tfh cellsPoster ExhibitionA32